When you’ve spent years treating patients in the emergency room, you see what happens when chronic conditions go unchecked. For Dr. Brian Spears, the shift from reactive medicine to preventative care wasn’t just professional, it was personal. Now as Chief Medical Officer at OrderlyMeds, he’s applying that hard-won insight to help patients pursue safe, effective weight loss with GLP-1 medications and evidence-backed support.
In this conversation, Dr. Spears shares how emergency medicine shaped his philosophy, why personalized oversight matters in today’s health landscape, and what every patient should know before starting GLP-1s.
A Front-Row Seat to the Risks of Waiting
Emergency medicine is reactive by nature. It was very eye-opening to see just how bad things can get when conditions like heart disease or diabetes go unmanaged.”
Dr. Brian Spears
Chief Medical Officer
His mindset began to shift during the height of the COVID-19 pandemic, when patients with chronic illness often had the poorest outcomes. That experience cemented his belief that early, preventative care isn’t just helpful—it’s essential.
Dr. Spears later transitioned into clinical research, exploring how medications could help people intervene earlier. Now at OrderlyMeds, he combines that research mindset with real-world caution, helping patients and OrderlyMeds navigate a fast-evolving weight loss landscape.
Guiding Patients Through a Noisy Health Space
We’re right on the edge of a new era in medicine. There are so many treatments being marketed—some exciting, some dangerous. My role is to help people sort the science from the snake oil.”
Dr. Brian Spears
Chief Medical Officer
With a surge in influencer-driven wellness content and social media hype around peptides and weight loss drugs, Dr. Spears encourages patients to stay skeptical and informed. “If you’re unsure, connect with a provider you trust or make sure you’re digging into real research before starting any new therapy.”
Why Rushing GLP-1s Can Backfire
One of the biggest misconceptions he sees? “That faster is better,” he says. “People want to jump to the highest GLP-1 dose right away to lose weight quickly. But that’s often when we see side effects, setbacks, and unsustainable progress.”
Instead, Dr. Spears advocates for a slow, measured ramp-up and a focus on lifestyle: eating more protein, doing resistance training, and preserving muscle mass. These habits will protect long-term metabolic health.
What Sets OrderlyMeds Apart
A lot of telehealth has turned into Amazon-style ordering, but we bring patients education, lifestyle support, and a whole-person approach that sets us apart.”
Dr. Brian Spears
Chief Medical Officer
Dr. Spears joined OrderlyMeds because the model goes beyond prescriptions. “A lot of telehealth has turned into Amazon-style ordering,” he says. “But we bring patients education, lifestyle support, and a whole-person approach that sets us apart.”
That includes guidance on nutrition, movement, mental health, and live orientation sessions— which Dr. Spears leads.
“Most medications are just band-aids,” he says. “But here, we’re doing the work to actually change the health trajectory of our patients.”
Want to hear more from Dr. Spears?
Considering GLP-1s? Start your journey with OrderlyMeds. Patients gain access to New Patient Orientation with Chief Medical Officer Dr. Brian Spears, plus expert guidance to begin safely and sustainably.



